貴邑冨久子 (田中冨久子) きむらふくこ たなかふくこ
(主な業績) Mitsushima
D, Takase K, Takahashi T, Kimura F. Activational
and organizational effects of gonadal steroids on sex-specific
acetylcholine release in the dorsal hippocampus.
J Neuroendocrinol, review article, in press,
2009.
Mitsushima D, Takase K, Funabashi T,
Kimura F. Gonadal steroids maintain 24-h acetylcholine
release in the hippocampus: organizational and activational
effects in behaving rats. J Neurosci, 29:
3808-3815, 2009.
Takase K, Kimura F, Yagami T, Mitsushima
D. Sex-specific 24-h acetylcholine release profile
in the medial prefrontal cortex: simultaneous measurement
of spontaneous locomotor activity in behaving rats.
Neuroscience, 159: 7-15, 2009.
Jitsuki S, Kimura F, Funabashi T, Takahashi
T, Mitsushima D. Sex-specific 24-h profile of extracellular
serotonin levels in the medial prefrontal cortex.
Brain Res, 1260: 30-37, 2009.
Takase K, Mitsushima D, Funabashi T,
Kimura F. Postpubertal feeding experience affects
sex-specific spatial ability in rats. Physiol
Behav, 93: 553-559, 2008.
Mitsushima
D, Takase K, Funabashi T, Kimura F. Gonadal steroid
hormones maintain the stress-induced acetylcholine release
in the hippocampus: simultaneous measurements of the
extracellular acetylcholine and serum corticosterone
levels in the same subjects. Endocrinology,149:
802-811, 2008.
Takase K, Mitsushima D, Funabashi T,
Kimura F. Sex difference in the 24-h acetylcholine
release profile in the premotor/supplementary motor
area of behaving rats. Brain Res, 1154:
105-115, 2007.
Takase K, Mitsushima D, Funabashi T,
Kimura F. Postpubertal feeding experience affects
sex-specific spatial abililty in rats. Physiol
Behav, 93: 553-559, 2007.
Fukushima A, Funabashi T, Kawaguchi
M, Mitsushima D, Kimura F. Bisphenol A induces
transforming growth factor-bata3 mRNA in the preoptic
area: a cDNA expression array and northern blot study.
Neurosci Lett, 411: 81-85, 2007.
Hagiwara H, Funabashi T, Mitsushima
D, Kimura F. Effects of neonatal testosterone
treatment on sex differences in formalin-induced nociceptive
behavior in rats. Neurosci Lett, 412: 264-267,
2007.
Shimamura, M., Shimizu, M., Yagami,
T., Funabashi, T., Kimura, F., Kuroiwa, Y., Misu, Y.,
Goshima, Y. l-3,4-Dihydroxyphenylalanine-induced
c-Fos expression in the CNS under inhibition of central
aromatic l-amino acid decarboxylase. Neuropharmacology,
50: 909-916, 2006.
Furuta, M., Funabashi, T., Kawaguchi,
M., Nakamura, T.J., Mitsushima, D., and Kimura,
F. Effects of p-Nonylphenol and 4-tert-Octylphenol
on the Anterior Pituitary Functions in Adult Ovariectomized
Rats. Neuroendocrinology, 84: 14-20, 2006.
Fukushima, A., Funabashi1, T., Kawaguchi,
M., Mitsushima, D., and Kimura, F. Bisphenol A
induces expression of transforming growth factor-b3
messenger ribonucleic acid in the medial preoptic area
of adult ovariectomized rats as revealed by cDNA expression
array. Neurosci Lett, 411: 81-85, 2006.
Mitsushima, D., Yamada, K., Takase,
K., Funabashi. T., and Kimura, F. Sex differences
in the basolateral amygdala: the extracellular level
of serotonin and dopamine and their responses to restraint
stress in rats. Eur J Neurosci, 24: 3245-3254,
2006.
Masuda, J., Mitsushima, D., Funabashi,
T., and Kimura, F. Sex and housing conditions
affect the 24-h acetylcholine release profile in the
hippocampus in rats. Neuroscience, 132:
537-542, 2005.
Funabashi, T., Sano, A., Mitsushima,
D., and Kimura, F. Nicotine inhibits pulsatile
luteinizing hormone secretion in human males but not
in human females, and tolerance to this nicotine effect
is lost within one week of quitting smoking. J
Clin Endocrinol Metab, 90: 3908-3931, 2005.
Mogi, K., Funabashi, T., Mitsushima,
D., Hagiwara, H., and Kimura. F. Sex difference
in the response of melanin-concentrating hormone neurons
in the lateral hypothalamic area to glucose, as revealed
by the expression of phosphorylated cyclic adenosine
3',5'-monophosphate response element-binding protein.
Endocrinology, 146: 3325-3333, 2005.
Takase, K., Funabashi, T., Mogi, K.,
Mitsushima, D., and Kimura, F. Feeding with powdered
diet after weaning increases visuospatial ability in
association with increases in the expression of N-methyl-d-aspartate
receptors in the hippocampus of female rats. Neurosci
Res, 53: 169-175, 2005.
Takase, K., Mitsushima, D., Masuda,
J., Mogi, K., Funabashi, T., Endo, Y., and Kimura, F.
Feeding with powdered diet after weaning affects sex
difference in acethylcholine release in the hippocampus
in rats. Neuroscience, 136: 593-599, 2005.
Funabashi, T., Kawaguchi, M., Furuta,
M., Fukushima, A., and Kimura, F. Exposure to
bisphenol A during gestation and lactation causes loss
of sex difference in corticotropin-releasing hormone-immunoreactive
neurons in the bed nucleus of the stria terminalis of
rats. Psychoneuroendocrinology, 29: 475-485,
2004.
Funabashi, T., Nakamura, T.J., and Kimura,
F. p-Nonylphenol, 4-tert-octylphenol and bisphenol
A increase the expression of progesterone receptor mRNA
in the frontal cortex of adult ovariectomized rats.
J Neuroendocrinol, 16: 99-104, 2004.
Kimura, F., Shinohara, K., Funabashi,
T., Daikoku, S., Suyama, K., Mitsushima, D., and Sano,
A. Nicotine inhibition of pulsatile GnRH secretion
is mediated by GABAA receptor system in the cultured
rat embryonic olfactory placode. Psychoneuroendocrinology,
29: 749-756, 2004.
Suyama, K., Daikoku, S., Funabashi,
T., and Kimura, F. Effects of GABA and bicuculline
on the electrical activity of rat olfactory placode
neurons derived at E13.5 and cultured for 1 week on
multi-electrode dishes. Endocr J, 51: 171-176,
2004.
Quan, H., Funabashi, T., and Kimura,
F. Intracerebroventricular injection of corticotropin-releasing
hormone receptor antagonist blocks the suppression of
pulsatile luteinizing hormone secretion induced by neuromedin
U in ovariectomized rats after 48 hours of fasting.
Neurosci Lett, 369: 33-38, 2004.
Funabashi, T., Sano, A., Mitsushima,
D., and Kimura, F. Bisphenol A increases progesterone
receptor immunoreactivity in the hypothalamus in a dose-dependent
manner and affects sexual behaviour in adult ovariectomized
rats. J Neuroendocrinol, 15: 134-140, 2003.
Mitsushima, D., Funabashi, T., Shinohara,
K., and Kimura, F. Rats living in small cages
respond to restraint stress with adrenocortical corticosterone
release but not with hippocampal acetylcholine release.
Psychoneuroendocrinology, 28: 574-583, 2003.
Mitsushima, D., Funabashi, T., and Kimura,
F. Estrogen increases messenger RNA and immunoreactivity
of aryl-hydrocarbon receptor nuclear translocator 2
in the rat mediobasal hypothalamus. Biochem
Biophy Res Comm, 307: 248-253, 2003.
Quan, H., Funabashi, T., Furuta, M.,
and Kimura, F. Effects of neuromedin U on the
pulsatile LH secretion in ovariectomized rats in association
with feeding conditions. Biochem Biophy Res Comm.,
311: 721-727, 2003.
Funabashi T, Sano A, Mitsushima D, Kimura
F. Bisphenol A increases progesterone receptor
immunoreactive cells in the hypothalamus in a dose-dependent
manner and affects sexual behavior in adult ovariectomized
rats. J Neuroendocrinology, 15: 134-140,
2003.
Mitsushima D, Funabashi T, Shinohara
K, Kimura F. Rats living in small cages respond
to restraint stress with adrenocortical corticosterone
release but not with hippocampal acetylcholine release.
Psychoneuroendocrinology, 28: 574-583, 2003.
Tin-Tin-Win-Shwe, Mitsushima D, Kimura
F. Profiles of in vivo GABA release in the medial
preoptic area of intact and castrated male rats.
Neuroendocrinology, 76: 290-296, 2002.
Mitsushima D, Tin-Tin-Win-Shwe, Funabashi
T, Shinohara K, Kimura F. GABA release in the
medial preoptic area of cyclic female rats. Neuroscience,
113(1):109-114, 2002 . PMID: 12123689
Shinohara K, Funabashi T, Nakamura TJ,
Mitsushima D, Kimura F. Differential regulation
of pituitary adenyl cyclase activating peptide receptor
variants in the rat suprachiasmatic nucleus. Neuroscience
2002;110(2):301-8. PMID: 11958871
Furuta M, Funabashi T, Kimura F.
Suppressive Action of Orexin A on Pulsatile Luteinizing
Hormone Secretion Is Potentiated by a Low Dose of Estrogen
in Ovariectomized Rats. Neuroendocrinology.
2002 Mar;75(3):151-157.
Furuta M, Funabashi T, Kimura F.
Intracerebroventricular administration of ghrelin rapidly
suppresses pulsatile luteinizing hormone secretion in
ovariectomized rats. Biochem Biophys Res Commun.
2001 Nov 9;288(4):780-5.
Nakamura TJ, Shinohara K, Funabashi
T, Kimura F. Effect of estrogen on the expression
of Cry1 and Cry2 mRNAs in the suprachiasmatic nucleus
of female rats. Neurosci Res. 2001 Nov;41(3):251-5.
Mitsushima D, He D, Funabashi T, Shinohara
K, Kimura F. Increase in the number of detectable
preoptic GAD67 immunoreactive cells in immature male
rats. Neurosci Res. 2001 May 40(2):141-146.
Mitsushima D, Funabashi T, Shinohara
K, Kimura F. Impairment of maze learning in rats
by restricting environmental space. Neurosci
Lett. 2001 Jan 12;297(2):73-6.
Funabashi T, Suyama K, Uemura T, Hirose
M, Hirahara F, Kimura F. Immortalized Gonadotropin-Releasing
Hormone Neurons (GT1-7 Cells) Exhibit Synchronous Bursts
of Action Potentials. Neuroendocrinology.
2001 Mar; 73(3): 157-165.
Shinohara K, Morofushi M, Funabashi
T, Kimura F. Axillary pheromones modulate pulsatile
LH secretion in humans. Neuroreport. 2001
Apr 17; 12(5): 893-5.
Sano A, Kimura F. Electrical activity
of the pulse generator of gonadotropin-releasing hormone
in 26-month-old female rats. Neuroendocrinology.
2000 Oct; 72(4): 199-207.
Funabashi T, Kleopoulos SP, Brooks PJ,
Kimura F, Pfaff DW, Shinohara K, Mobbs CV. Changes
in estrogenic regulation of estrogen receptor alpha
mRNA and progesterone receptor mRNA in the female rat
hypothalamus during aging: an in situ hybridization
study. Neurosci Res. 2000, Sep; 38(1):
85-92.
Shinohara K, Funabashi T, Mitushima
D, Kimura F. Effects of gap junction blocker on
vasopressin and vasoactive intestinal polypeptide rhythms
in the rat suprachiasmatic nucleus in vitro. Neurosci
Res. 2000 Sep; 38(1): 43-7.
Shinohara K, Morofushi M, Funabashi
T, Mitsushima D, Kimura F. Effects of 5alpha-androst-16-en-3alpha-ol
on the pulsatile secretion of luteinizing hormone in
human females. Chem Senses. 2000, Aug;
25(4) : 465-7.
Morofushi M, Shinohara K, Funabashi
T, Kimura F. Positive relationship between menstrual
synchrony and ability to smell 5alpha-androst-16-en-3alpha-ol.
Chem Senses. 2000, Aug; 25(4 ):407-11.
Funabashi T, Shinohara K, Mitsushima
D, Kimura F. Gonadotropin-releasing hormone exhibits
circadian rhythm in phase with arginine-vasopressin
in co-cultures of the female rat preoptic area and suprachiasmatic
nucleus. J Neuroendocrinol. 2000, Jun;
12(6): 521-8.
Shinohara K, Funabashi T, Mitushima
D, Kimura F. Effects of estrogen on the expression
of connexin32 and connexin43 mRNAs in the suprachiasmatic
nucleus of female rats. Neurosci Lett. 2000,
Jun 2; 286(2): 107-10.
Funabashi T, Shinohara K, Mitsushima
D, Kimura F. Estrogen increases arginine-vasopressin
V1a receptor mRNA in the preoptic area of young but
not of middle-aged female rats. Neurosci Lett.
2000 May 19;285(3):205-8.
Saito K, Shinohara K, Morofushi M, Funabashi
T, Mitsushima D, Hata M, Matsubara S, Kimura F.
Effects of irradiation on the sensitivity of melatonin
release to norepinephrine in cultured pineal bodies
of rats. Neurosci Lett. 2000 Apr 21;284(1-2):93-6.
Funabashi T, Jinnai K, Sano A, Shinohara
K, Kimura F. Pentobarbital stimulates the activity
of the GnRH pulse generator interacting with opioid
neurons in rats in proestrus. Psychoneuroendocrinology.
2000 Apr;25(3):277-87.
Shinohara K, Hiruma H, Funabashi T,
Kimura F. GABAergic modulation of gap junction
communication in slice cultures of the rat suprachiasmatic
nucleus. Neuroscience. 2000;96(3):591-6.
Shinohara K, Uchiyama M, Okawa M, Saito
K, Kawaguchi M, Funabashi T, Kimura F. Menstrual
changes in sleep, rectal temperature and melatonin rhythms
in a subject with premenstrual syndrome. Neurosci
Lett. 2000 Mar 10;281(2-3):159-62.
He D, Mitsushima D, Uemura T, Hirahara
F, Funabashi T, Shinohara K, Kimura F. Effects
of naloxone on the serum luteinizing hormone level and
the number of Fos-positive gonadotropin-releasing hormone
neurons in immature female rats. Brain Res.
2000 Mar 6;858(1):129-35.
Funabashi T, Daikoku S, Shinohara K,
Kimura F. Pulsatile gonadotropin-releasing hormone
(GnRH) secretion is an inherent function of GnRH neurons,
as revealed by the culture of medial olfactory placode
obtained from embryonic rats. Neuroendocrinology.
2000 Feb;71(2):138-44.
Akema T, Ikeda T, Chiba A, Sugiyama
H, Sato I, Kimura F, Toyoda J. Intraventricular
injection of melatonin inhibits naloxone-induced, but
not NMDA- or LHRH-induced LH release in ovariectomized
estrogen-primed rats. Endocr J. 1999, Dec;
46(6): 831-6.
Mitsushima D, Funabashi T, Kimura F.
Fos expression in gonadotropin-releasing hormone neurons
by naloxone or bicuculline in intact male rats.
Brain Res. 1999, Aug 21; 839(1): 209-12.
Sano A, Funabashi T, Kawaguchi M, Shinohara
K, Kimura F. Intravenous injections of nicotine
decrease the pulsatile secretion of LH by inhibiting
the gonadotropin-releasing hormone (GnRH) pulse generator
activity in female rats. Psychoneuroendocrinology,
1999, May;24(4): 397-407.
Nishimura J, Endo Y, Kimura F.
A long-term stress exposure impairs maze learning performance
in rats. Neurosci Lett, 1999, Oct 1;273(2):
125-8.
Endo Y, Nishimura JI, Kobayashi S, Kimura
F. Chronic stress exposure influences local cerebral
blood flow in the rat hippocampus. Neuroscience.
1999;93(2):551-5.
Funabashi T, Aiba S, Sano A, Shinohara
K, Kimura F. Intracerebroventricular injection
of arginine-vasopressin V1 receptor antagonist attenuates
the surge of luteinizing hormone and prolactin secretion
in proestrous rats. Neurosci Lett. 1999
Jan 22;260(1):37-40.
Gerkema MP, Shinohara K, Kimura F.
Lack of circadian patterns in vasoactive intestinal
polypeptide release and variability in vasopressin release
in vole suprachiasmatic nuclei in vitro. Neurosci
Lett. 1999 Jan 8;259(2):107-10.
He D, Funabashi T, Sano A, Uemura T,
Minaguchi H, Kimura F. Effects of glucose and
related substrates on the recovery of the electrical
activity of gonadotropin-releasing hormone pulse generator
which is decreased by insulin-induced hypoglycemia in
the estrogen-primed ovariectomized rat. Brain
Res. 1999 Feb 27;820(1-2):71-6.
Hla-Hla-Aye, Jinnai K, Sano A, Funabashi
T, Mitsushima D, Kimura F. Nicotine given intracerebroventricularly
does not inhibit the preovulatory surge of LH and PRL
secretion in female rats. Endocr J. 1998
Aug;45(4):575-80.
Shinohara K, Funabashi T, Kimura F.
Temporal profiles of vasoactive intestinal polypeptide
precursor mRNA and its receptor mRNA in the rat suprachiasmatic
nucleus. Brain Res Mol Brain Res. 1999
Jan 8;63(2):262-7.
Kawaguchi M, Funabashi T, Kimura F.
Insulin-induced hypoglycemia does not impair the surge
of luteinizing hormone secretion in the proestrous rat.
Neurosci Lett. 1998 Nov 13;256(3):131-4.
Funabashi T, Kleopoulos SP, Kimura F,
Mobbs CV. Changes in neurotensin mRNA by estrogen
in the female rat preoptic area during aging: an in
situ hybridization histochemistry study. Gen
Comp Endocrinol. 1998 Dec;112(3):364-71.
Mitsushima D, Yamanoi C, Kimura F.
Restriction of environmental space attenuates locomotor
activity and hippocampal acetylcholine release in male
rats. Brain Res. 1998 Sep 14;805(1-2):207-12.
Chiba A, Akema T, Iigo M, Nagami Y,
Kimura F, Toyoda J. A possible role of the pineal
gland in acute immobilization-related suppression of
naloxone-induced LH release in ovariectomized estrogen-primed
rats. J Neuroendocrinol. 1998 Feb;10(2):79-84.
Akema T, Chiba A, Ikeda T, Nagami Y,
Kimura F, Toyoda J. Melatonin inhibits naloxone-induced
luteinizing hormone release in ovariectomized estrogen-primed
rats. J Neuroendocrinol. 1997 Nov;9(11):849-57.
Mitsushima D, Jinnai K, Kimura F.
Possible role of the gamma-aminobutyric acid-A receptor
system in the timing of the proestrous luteinizing hormone
surge in rats. Endocrinology. 1997 May;138(5):1944-8.
Mitsushima D, Kimura F. The maturation
of GABA(A) receptor-mediated control of luteinizing
hormone secretion in immature male rats. Brain
Res. 1997 Feb 14;748(1-2):258-62.
Chiba A, Akema T, Nagami Y, Kimura F,
Toyoda J. Differential inhibition of NMDA- and
naloxone-induced LH release by NMDA receptor antagonist
and CRH in ovariectomized estrogen-primed rats.
Neuroendocrinology. 1997 Feb;65(2):141-6.
Funabashi T, Jinnai K, Kimura F.
Bicuculline infusion advances the timing of Fos expression
in LHRH neurons in the preoptic area of proestrous rats.
Neuroreport. 1997 Feb 10;8(3):771-4.
Funabashi T, Jinnai K, Kimura F.
Fos expression by naloxone in LHRH neurons of the mediobasal
hypothalamus and effects of pentobarbital sodium in
the proestrous rat. J Neuroendocrinol.
1997 Feb;9(2):87-92.
Hiruma H, Uemura T, Kimura F.
Neuronal synchronization and ionic mechanisms for propagation
of excitation in the functional network of immortalized
GT1-7 neurons: optical imaging with a voltage-sensitive
dye. J Neuroendocrinol. 1997 Nov;9(11):835-40.
Uemura T, Nishimura J, Yamaguchi H,
Hiruma H, Kimura F, Minaguchi H. Effects of noradrenaline
on GnRH-secreting immortalized hypothalamic (GT1-7)
neurons. Endocr J. 1997 Feb;44(1):73-8.
Endo Y, Nishimura JI, Kobayashi S, Kimura
F. Long-term glucocorticoid treatments decrease
local cerebral blood flow in the rat hippocampus, in
association with histological damage. Neuroscience.
1997 Aug;79(3):745-52.
Mizuno T, Kimura F. Attenuated
stress response of hippocampal acetylcholine release
and adrenocortical secretion in aged rats. Neurosci
Lett. 1997 Jan 24;222(1):49-52.
Noguchi K, Arita J, Nagamoto A, Hosaka
M, Kimura F. A quantitative analysis of testosterone
action on FSH secretion from individual pituitary cells
using the cell immunoblot assay. J Endocrinol.
1996 Mar;148(3):427-33.
Endo Y, Nishimura JI, Kimura F.
Impairment of maze learning in rats following long-term
glucocorticoid treatments. Neurosci Lett. 1996
Jan 26;203(3):199-202.
Mitsushima D, Mizuno T, Kimura F.
Age-related changes in diurnal acetylcholine release
in the prefrontal cortex of male rats as measured by
microdialysis. Neuroscience. 1996 May;72(2):429-34.
Mizuno T, Kimura F. Medial septal
injection of naloxone elevates acetylcholine release
in the hippocampus and induces behavioral seizures in
rats. Brain Res. 1996 Mar 25;713(1-2):1-7.
Akema T, Chiba A, Shinozaki R, Oshida
M, Kimura F, Toyoda J. Acute immobilization stress
and intraventricular injection of CRF suppress naloxone-induced
LH release in ovariectomized estrogen-primed rats.
J Neuroendocrinol. 1996 Aug;8(8):647-52.
Akema T, Chiba A, Oshida M, Kimura F,
Toyoda J. Permissive role of corticotropin-releasing
factor in the acute stress-induced prolactin release
in female rats. Neurosci Lett. 1995 Sep
29;198(2):146-8.
Akema T, Chiba A, Shinozaki R, Oshida
M, Kimura F, Toyoda J. Acute stress suppresses
the N-methyl-D-aspartate-induced luteinizing hormone
release in the ovariectomized estrogen-primed rat.
Neuroendocrinology. 1995 Sep;62(3):270-6.
Kimura F, Jinnai K, Sano A. LHRH
pulse generator is stimulated by naloxone in the pentobarbital-blocked
proestrous rat. J Neuroendocrinol. 1995
Dec;7(12):917-22.
Kimura F, Sano A. The effect of
pentobarbital on the electrical activity of LHRH pulse
generator in the ovariectomized rat with or without
estrogen priming. J Neuroendocrinol. 1995
Dec;7(12):911-5.
Hiruma H, Kimura F. Luteinizing
hormone-releasing hormone is a putative factor that
causes LHRH neurons to fire synchronously in ovariectomized
rats. Neuroendocrinology. 1995 May;61(5):509-16.
Funabashi T, Kimura F. The number
of luteinizing hormone-releasing hormone immunoreactive
neurons is significantly decreased in the forebrain
of old-aged female rats. Neurosci Lett. 1995
Apr 14;189(2):85-8.
Kojima Y, Arita J, Kuwana N, Kimura
F. Dopamine responsiveness of human prolactinoma
cells as determined by the reverse hemolytic plaque
assay. Endocr J. 1995 Jun;42(3):355-60.
Arita J, Kojima Y, Yamamoto I, Mazawa
S, Kimura F. Somatotropes and thyrotropes in the
rat anterior pituitary gland cosecrete substance P:
analysis by the sandwich cell immunoblot assay.
Neuroendocrinology. 1994 Dec;60(6):567-74.
Kato A, Hiruma H, Kimura F. Acute
estradiol modulation of electrical activity of the LHRH
pulse generator in the ovariectomized rat: restoration
by naloxone. Neuroendocrinology. 1994 May;59(5):426-31.
Nishihara M, Sano A, Kimura F.
Cessation of the electrical activity of gonadotropin-releasing
hormone pulse generator during the steroid-induced surge
of luteinizing hormone in the rat. Neuroendocrinology.
1994 Jun;59(6):513-9.
Endo Y, Nishimura J, Kimura F.
Adrenalectomy increases local cerebral blood flow in
the rat hippocampus. Pflugers Arch. 1994
Feb;426(3-4):183-8.
Hiruma H, Sano A, Kimura F. Injection
of bicuculline elicits firing of luteinizing hormone
releasing hormone pulse generator in muscimol-treated
ovariectomized rats. Brain Res. 1994 Apr
4;641(2):191-7.
Funabashi T, Hashimoto R, Jinnai K,
Kimura F. Microinjection of LHRH and its antagonistic
analog into the medial preoptic area does not affect
pulsatile secretion of LH in ovariectomized rats.
Endocr J. 1994 Oct;41(5):559-63.
Endo Y, Mizuno T, Fujita K, Funabashi
T, Kimura F. Soft-diet feeding during development
enhances later learning abilities in female rats.
Physiol Behav. 1994 Oct;56(4):629-33.
Mizuno T, Arita J, Kimura F. Spontaneous
acetylcholine release in the hippocampus exhibits a
diurnal variation in both young and old rats.
Neurosci Lett. 1994 Sep 12;178(2):271-4.
Mizuno T, Ito E, Kimura F. Pentobarbital
sodium inhibits the release of noradrenaline in the
medial preoptic area in the rat. Neurosci Lett.
1994 Mar 28;170(1):111-3.
Funabashi T, Kimura F. Effects
of estrogen and estrogen receptor messenger RNA levels
in young and middle-aged female rats: comparison of
medial preoptic area and mediobasal hypothalamus.
Acta Biol Hung. 1994;45(2-4):223-31.
Kimura F, Jinnai K, Funabashi T.
A GABAB-receptor mechanism is involved in the prolactin
release in both male and female rats. Neurosci
Lett. 1993 Jun 11;155(2):183-6.
Kimura F, Sano A, Hiruma H, Funabashi
T. Effects of gamma-aminobutyric acid-A receptor
antagonist, bicuculline, on the electrical activity
of luteinizing hormone-releasing hormone pulse generator
in the ovariectomized rat. Neuroendocrinology.
1993 Apr;57(4):605-14.
Arita J, Kojima Y, Kimura F. Measurement
of the secretion of a small peptide at the single cell
level by the cell immunoblot assay: thyroidectomy increases
the number of substance P-secreting anterior pituitary
cells. Endocrinology. 1993 Jun;132(6):2682-8.
Akema T, Kimura F. Differential
effects of GABAA and GABAB receptor agonists on NMDA-induced
and noradrenaline-induced luteinizing-hormone
release in the ovariectomized estrogen-primed rat.
Neuroendocrinology. 1993 Jan;57(1):28-33.
Tanaka J, Nomura M, Kariya K, Nishimura
J, Kimura F. Median preoptic neurons projecting
to the hypothalamic paraventricular nucleus are sensitive
to blood pressure changes. Brain Res. 1993
Mar 12;605(2):338-41.
Tanaka J, Nishimura J, Kimura F, Nomura
M. Noradrenergic excitatory inputs to median preoptic
neurones in rats. Neuroreport. 1992 Oct;3(10):946-8.
Akema T, Kimura F. Modulation
of pulsatile LH secretion by baclofen, a selective GABAB
receptor agonist, in ovariectomized rats. Neuroendocrinology.
1992 Aug;56(2):141-7.
Arita J, Kojima Y, Kimura F. Lactotrophs
secreting small amounts of prolactin reveal great responsiveness
to thyrotropin-releasing hormone: analysis by the sequential
cell immunoblot assay. Endocrinology. 1992
Jun;130(6):3167-74.
Hiruma H, Nishihara M, Kimura F.
Hypothalamic electrical activity that relates to the
pulsatile release of luteinizing hormone exhibits diurnal
variation in ovariectomized rats. Brain Res.
1992 Jun 5;582(1):119-22.
Nishimura J, Endo Y, Kimura F.
Increases in cerebral blood flow in rat hippocampus
after medial septal injection of naloxone. Stroke.
1992 Sep;23(9):1325-9;
Mizuno T, Endo Y, Arita J, Kimura F.
Acetylcholine release in the rat hippocampus as measured
by the microdialysis method correlates with motor activity
and exhibits a diurnal variation. Neuroscience.
1991;44(3):607-12.
Akema T, Kimura F. The mode of
GABAB receptor-mediated inhibition of the preovulatory
luteinizing hormone surge in female rats. Brain
Res. 1991 Oct 18;562(1):169-72.
Akema T, Kimura F. 2-Hydroxysaclofen,
a potent GABAB receptor antagonist, stimulates luteinizing
hormone secretion in female rats. Brain Res.
1991 Apr 12;546(1):143-5.
Arita J, Kojima Y, Kimura F. Identification
by the sequential cell immunoblot assay of a subpopulation
of rat dopamine-unresponsive lactotrophs. Endocrinology.
1991 Apr;128(4):1887-94.
Arita J, Hashimoto R, Kimura F.
The activity of catecholamine synthesis in the hypothalamus
of female normotensive Wistar Kyoto and spontaneously
hypertensive rats. Brain Res. 1991 Mar
8;543(1):157-9.
Nishihara M, Hiruma H, Kimura F.
Interactions between the noradrenergic and opioid peptidergic
systems in controlling the electrical activity of luteinizing
hormone-releasing hormone pulse generator in ovariectomized
rats. Neuroendocrinology. 1991 Oct;54(4):321-6.
Hashimoto R, Sano A, Nishimura J, Funabashi
T, Kimura F. Naloxone injected into the preoptic
region has hypophysiotropic and seizurogenic actions
in rats. Endocrinol Jpn. 1991 Jun;38(3):287-95.
Endo M, Arita J, Fujita K, Kimura F.
Mechanism for the cardiovascular action of intracerebroventricularly
administered vasoactive intestinal polypeptide in rats.
Exp Clin Endocrinol. 1991 Mar;97(1):55-62.
Funabashi T, Hiruma H, Arita J, Kimura
F. Intraventricular injection of vasoactive intestinal
polypeptide facilitates the development of amygdaloid
kindling. Brain Res. 1991 Feb 8;541(1):110-4.
Kimura F, Nishihara M, Hiruma H, Funabashi
T. Naloxone increases the frequency of the electrical
activity of luteinizing hormone-releasing hormone pulse
generator in long-term ovariectomized rats. Neuroendocrinology.
1991 Jan;53(1):97-102.
Hashimoto R, Kimura F. Long-term
depressor effects of catecholamine neuronal grafts in
the third ventricle of the brain in normotensive rats.
Experientia. 1991 Jun 15;47(6):619-22.
Hashimoto R, Kimura F. Effects
of intraventricular injection of delta receptor antagonist
ICI 154, 129 on the secretion of luteinizing hormone
and prolactin in the proestrous rat. Endocrinol
Jpn. 1991 Apr;38(2):213-8. |