横浜市立大学大学院・医学研究科 生理学














教室員の紹介

多田 敬典 (ただ ひろぶみ)


(主な業績)


Tada H, Miyazaki T,Takemoto K, Jitsuki S, Nakajima W, Koide M, Yamamoto N, Taguchi A, Kawai H, Komiya K, Suyama K, Abe H, Sano A and Takahashi T.
Social isolation suppresses actin dynamics and synaptic plasticity through ADF/cofilin inactivation in the developing rat barrel cortex.
Scientific Reports, Article number: 8471 (2017) ,
doi
:10.1038/s41598-017-08849-3 .

Tada H, Miyazaki T, Takemoto K, Takase K, Jitsuki S, Nakajima W, Koide M, Yamamoto N, Komiya K, Suyama K, Sano A, Taguchi A, and Takahashi T
Neonatal isolation augments social dominance by altering actin dynamics in the medial prefrontal cortex
Proc Natl Acad Sci USA.,1606351113, 2016


Tada H, Koide M, Ara W, Shibata Y, Funabashi T, Suyama K, Goto T, Takahashi T.
Estrous Cycle-Dependent Phasic Changes in the Stoichiometry of Hippocampal Synaptic AMPA Receptors in Rats.
Plos One, 2015 Jun 29;10(6):e0131359. doi: 10.1371/journal.pone.0131359
.


Tada H, Kuroki Y, Funabashi T, Kamiya Y, Goto T, Suyama K, Sano A, Mitsushima D, Etgen AM, Takahashi T.
Phasic synaptic incorporation of GluR2-lacking AMPA receptors at gonadotropin-releasing hormone neurons is involved in the generation of the luteinizing hormone surge in female rats.
Neuroscience, 248: 664-669, 2013.

 

Miyazaki T, Takase K, Nakajima W, Tada H, Ohya D, Sano A, Goto T, Hirase H, Malinow R, Takahashi T.
Disrupted cortical function underlies behavior dysfunction due to social isolation.
122(7): 2690-701, 2012.

 

Renault-Mihara F, Katoh H, Ikegami T, Iwanami A, Mukaino M, Yasuda A, Nori S, Mabuchi Y, Tada H, Shibata S, Saito K, Matsushita M, Kaibuchi K, Okada S, Toyama Y, Nakamura M, Okano H.
Beneficial compaction of spinal cord lesion by migrating astrocytes through glycogen synthase kinase-3 inhibition.Beneficial compaction of spinal cord lesion by migrating astrocytes through glycogen synthase kinase-3 inhibition.
EMBO Mol Med., 3(11): 682-96, 2011.

 

Jitsuki S, Takemoto K, Kawasaki T, Tada H, Takahashi A, Becamel C, Sano A, Yuzaki M, Zukin RS, Ziff EB, Kessels HW, and Takahashi T.
Serotonin mediates cross-modal reorganization of cortical circuits.
Neuron, 69(4): 780-92, 2011.

 

Sakaguchi M, Imaizumi Y, Shingo T, Tada H, Hayama K, Yamada O, Morishita T, Kadoya T, Uchiyama N, Shimazaki T, Kuno A, Poirier F, Hirabayashi J, Sawamoto K, Okano H.

"Regulation of adult neural progenitor cells by Galectin-1/beta1 Integrin interaction."

J Neurochem., 113(6): 1516-24, 2010.

 

Tada H, Okano HJ, Takagi H, Shibata S, Yao I, Matsumoto M, Saiga T, Nakayama KI, Kashima H, Takahashi T, Setou M, Okano H.

"Fbxo45, a novel ubiquitin ligase, regulates synaptic activity."

J. Biol. Chem., 285(6): 3840-9, 2010.

 

Saiga T, Fukuda T, Matsumoto M, Tada H, Okano HJ, Okano H, Nakayama KI.

"Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development."

Mol Cell Biol., 29(13): 3529-43, 2009.

 

Tada H, Ishi S, Kimura H, Hattori H, Okada Y, Suzuki N, Okano HJ.

"Identification and Evaluation of High-titer Anti-Sox Group B Antibody in Limbic Encephalitis."

Inflammation and Regeneration, 27(1): 37-44, 2007.