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Kiwamu Takemoto
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@(Assistant Professor )

Publications

17. Takemoto K*, Iwanari H, Tada H, Suyama K, Sano A, Nagai T, Hamakubo T, and Takahashi T.*
"Optical inactivation of synaptic AMPA receptors erases fear memory"
Nat. Biotechnol., 35(1);38-47, 2017 (*co-corresponding author)
See also NEWS AND VIEWS

16. Tada H, Miyazaki T,
Takemoto K, Takase K, Jitsuki S, Nakajima W, Koide M, Yamamoto N, Komiya K, Suyama K, Sano A, Taguchi A, and Takahashi T
"Neonatal isolation augments social dominance by altering actin dynamics in the medial prefrontal cortex"
Proc Natl Acad Sci U S A.,1606351113, 2016

15. Sakamaki K, Ishii MT, Sakata T,
Takemoto K, Takagi C, Takeuchi A, Morishita R, Takahashi H, Nozawa A, Shinoda H, Chiba K, Sugimoto H, Saito A, Tamate S, Satou Y, Sang-Kee J, Matsuoka S, Koyamada K, Sawasaki T, Nagai T, Ueno N
"Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage"
Biochem.Biophys.Acta., 1863(11);2766-2783, 2016

14. Jitsuki S, Nakajima W, Takemoto K , Sano A, Tada H, Takahashi-Jitsuki A, Takahashi T.
"Nogo Receptor Signaling Restricts Adult Neural Plasticity by Limiting Synaptic AMPA Receptor Delivery"
Cerebral Cortex, 26(1); 427-439, 2016

13. Liu T, Yamaguchi Y, Shirasaki Y, Shikada K, Hoshino K, Kaisho T, Takemoto K , Suzuki T, Kuranaga E, Ohara O, Miura M.
"Single-cell imaging of caspase-1 dynamics reveals an all-or none inflammasome signaling responce"
Cell Rep.8(4):974-982, 2014.

12. Yamaguchi Y, Kuranaga E, Nakajima Y, Koto A, Takemoto K, Miura M.
"In vivo monitoring of caspase activation using a fluorescence resonance energy transfer-based fluorescent probe"
Methods Enzymol., 544; 299-325, 2014.

11. Takemoto K , Matsuda T, Sakai N, Fu D, Noda M, Uchiyama S, Kotera I, Arai Y, Horiuchi M, Fukui K, Ayabe T, Inagaki F, Suzuki H, Nagai T.
"SuperNova, a monomeric photosensitizing fluorescent protein for chromophore-assisted light inactivation"
Sci. Rep., 3; 2629, 2013.

10. Ohtsuka K, Sato S, Sato Y, Sota K, Ohzawa S, Matsuda T, Takemoto K, Takamune N, Juskowiak B, Nagai T, Takenaka S
"Fluorescence imaging of potassium ions in living cells using a fluorescent probe based a thrombin binding aptamer-peptide conjyugate"
Chem. Commun. 48(39):4740-2, 2012.

9. Yamaguchi Y, Shinotsuka N, Nonomura K, Takemoto K , Kuida K, Yoshida H, Miura M.
gLive imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closureg
J.Cell.Biol. 195(6): 1047-60, 2011.

8. Takemoto K , Matsuda T, McDougall M, Klaubert DH, Hasegawa A, Los GV, Wood KV, Miyawaki A, Nagai T.
gChromophore-assisted light inactivation of HaloTag fusion proteins labeled with eosin in living cellsg
ACS Chem Biol. 6(5): 401-6, 2011.

7. Kuranaga E, Matsunuma T, Kanuka H, Takemoto K , Koto A, Kimura K, Miura M.
"Apotosis controls the speed of looping morphogenesis in Drosophila male terminalia"
Development. 138(8): 1493-9, 2011.

6. Jitsuki S, Takemoto K , Kawasaki T, Tada H, Takahashi A, Becamel C, Sano A, Yuzaki M, Zukin RS, Ziff EB, Kessels HW, and Takahashi T.
"Serotonin mediates cross-modal reorganization of cortical circuits".
Neuron, 69, 780-792, 2011.

5. Takemoto K , Kuranaga E, Tonoki A, Nagai T, Miyawaki A and Miura M.
gLocal initiation of caspase activation in Drosophila salivary gland programmed cell death in vivo g
Proc Natl Acad Sci U S A. 104(33): 13367-13372, 2007.
 

4. Kuranaga E, Kanuka H, Tonoki A, Takemoto K , Tomioka T, Kobayashi M, Hayashi S and Miura M.
gDrosophila IKK-Related Kinase regulates non-apoptotic function of caspases via degradation of IAPsh
Cell 126(3): 583-596, 2006.

3. Kanuka H., Kuranaga E., Takemoto K ., Hiratou T., Okano H., and Miura M.
gDrosophila caspase transduces Shaggy/GSK-3b kinase activity in neural precuorsor development.h
EMBO J. 24(21): 3793-3806, 2005.

2.Takemoto K , Nagai T, Miyawaki A, and Miura M.
gSpatio-temporal activation of caspase revealed by indicator that is insensitive to environmental effectsh
J.Cell Biol. 160(2): 235-243, 2003.

See also In This Issue.

1. Uetsuki T, Takemoto K , Nishimura I, Okamoto M, Niinobe M, Momoi T, Miura M and Yoshikawa K.
gActivation of Neuronal Caspase-3 by Intracellular Accumulation of Wild-Type Alzheimer Amyloid Precursor Proteinh
J.Neurosci. 19(16): 6955-6964, 1999.